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The cation is stabilized by interacting with lone pairs of electrons on the surrounding oxygen atoms

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Briefly, cardiac tissues were homogenized in 250 mM HEN buffer (250 mM Hepes, 1 mM EDTA, 0.1 mM neocuproine and 100 M deferoxamine) and centrifuged at 13,000 g for 30 min at 4 C